CSIR-CCMB develops India-specific tool to predict sickle cell severity

Hyderabad: Doctors may soon have a more reliable way to predict how severely sickle cell anaemia (SCA) will affect Indian patients.

Scientists at the CSIR-Centre for Cellular and Molecular Biology (CCMB) have developed a new India-specific disease severity score using clinical data from Indian children.

Researchers analysed the medical records of 171 children, aged up to 18 years, with sickle cell anaemia and receiving treatment at the Government Medical College and Hospital, Nagpur.

The new tool could improve treatment decisions and disease management as existing international scoring systems do not accurately reflect the clinical profile of Indian patients with SCA, whose disease patterns often differ from those seen in African and Western populations.